Joe Biden has welcomed the administration of the 50 millionth dose of Covid-19 vaccine since his swearing-in.

The moment came days after the US reached the devastating milestone of 500,000 coronavirus deaths and ahead of a meeting with the nation’s governors on plans to speed the distribution of vaccines even further.

“The more people get vaccinated, the faster we’re going to beat this pandemic,” Mr Biden said at the White House ceremony, noting that his administration is on course to exceed his promise to deliver 100 million shots in his first 100 days in office.

“We’re halfway there: 50 million shots in 37 days,” Mr Biden said. “That’s weeks ahead of schedule.”

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President Joe Biden talks to Linda Bussey before she received a vaccination (Evan Vucci/AP)

All told, more than 45 million Americans have been given at least one dose of the approved vaccines from Pfizer and Moderna since they received approval from the Food and Drug Administration in December, with more than 20 million receiving both required doses.

As part of the ceremony, four frontline workers — a pair of emergency medical technicians, a school counsellor and a grocery store worker — received vaccine doses on live television, part of the White House’s efforts to build confidence in the vaccination programme.

Mr Biden predicts that by late spring there will be enough vaccine to administer to anyone that wants it, but that hesitance of the vaccine will limit the number of people who want it.

“We’ll have the vaccine waiting,” Mr Biden said, predicting that point could come within 60 to 90 days.

He promised a “massive campaign to educate people” about the safety and efficacy of the vaccines, in the hope of stimulating demand as the nation aims to vaccinate about 80% of adults to reach herd immunity and end the pandemic.

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President Joe Biden looks on as Victoria Legerwood Rivera receives a vaccination (Evan Vucci/AP)

Mr Biden said he planned to tour a US military-run mass vaccination site in Houston on Friday, one of several ways his administration is aiming to speed injections, particularly once supply increases.

Mr Biden noted the promise of a third vaccine receiving approval as soon as this weekend, as Johnson & Johnson’s single-dose candidate undergoes review by the FDA.

“We have a plan to roll it out as quickly as Johnson & Johnson can make it,” Mr Biden said.

Meeting with governors, Mr Biden appealed for their help in passing his 1.9 trillion dollar “American Rescue Plan,” which provides funding to expand vaccination and testing as well as economic relief for people struggling during the pandemic.

“The economic toll of this pandemic continues to tear through our country as brutally as the virus itself,” Mr Biden said.

He also warned that variants could continue to spread, leading to more cases and hospitalisations. He appealed to Americans to keep up with social distancing measures and wear face coverings.

“This is not the time to relax,” he said.