Cray Wanderers were beaten 2-1 at Carshalton Athletic after Luke Nolan fired an 83rd minute winner for the home side.
The Wands have now lost four consecutive games in the Ryman Premier League since the start of January, and have slipped to 14th in the table.
Cray manager Ian Jenkins will look to revive and rebuild his team after a recent spate of player injuries and departures.
The brothers Joe and Paul Vines have left the club, and key midfielder Danny Phillips is out with a dislocated shoulder.
Phillips suffered his injury in the early minutes of Cray's 5-1 defeat at Thurrock on Tuesday night, where Cray were soon afterwards reduced to ten men when Joe Vines was sent off.
Cray also have defenders Aaron Day and Danny Young on the injury list, although midfielder Chris Saunders was passed fit to play at Carshalton after missing three games.
The Wands have also signed left-sided defender Matt Pooley who has returned to the club after playing a few games at the start of the season.
At Carshalton the Wands took the lead on 26 minutes when Leigh Bremner earned a penalty-kick and netted it himself.
Bremner had earlier gone close for Cray on two occasions, but Carshalton levelled on 31 minutes from Hakeem Adelukan.
Bremner hit the post for Cray before the interval.
The second half saw chances arrive at both ends, before Cray suffered two late misfortunes.
Nolan struck the winner for Carshalton and Cray skipper Mark Willy was sent off shortly afterwards for a tackle that conceded a free-kick just outside the box.
Cray; Walker, Burgess, Pooley, Saunders, Willy, Sterling, Fray, Stavrinou, Bremner, Power, Clark. Subs: Parkinson, Fasunan, Estrada, Taylor, Hall.
Cray are at home to Bognor Regis Town on Tuesday (7.45pm) and home to Enfield Town next Saturday (3pm).