The 15-year-old boy was reported as missing after he did not return to his Felspar Close home following his last sighting at a Thamesmead academy.
Odayne Gayle has not been seen since he attended Woolwich Polytechnic School, in Hutchins Road, on Friday, January 27.
Greenwich police said they were increasingly concerned about the child’s wellbeing.
When he vanished the teenager was wearing black trousers, white shirt, Woolwich Polytechnic blazer, burgundy stripped tie and black school shoes.
If you have any information call police on 101, or Missing People on 116000.
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