Train passengers travelling to London from Kent and the south-east face disruption from Easter engineering works.
Work on signals and tracks at London Bridge station will cause delays until Monday.
Southeastern, First Capital Connect and Southern services into the capital will be affected.
No trains will stop at Charing Cross, Waterloo East or London Bridge until Monday morning.
Southeastern services will instead be diverted into Cannon Street.
Trains between Sole Street, Strood and Gillingham will also be closed over the weekend, affecting Chatham line services into Victoria, Charing Cross and St Pancras.
There will be no trains between Victoria and Dartford, Southeastern have said.
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